CRBN ligand-704

Catalog No.: A80566
Ligand for E3 Ligase
CRBN ligand-704 is a ligand for the E3 ubiquitin ligase cereblon (CRBN). It effectively recruits the CRBN protein for targeted protein degradation applications, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). Its utility in research enables the selective modulation of protein levels, making it a valuable tool for studies in protein homeostasis and therapeutic development.
Grouped product items
Size Price Stock Qty
50mg
$125.00
In stock
100mg
$200.00
In stock
250mg
$320.00
In stock
500mg
$505.00
In stock
1g
$805.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCRBN ligand-704 is a ligand for the E3 ubiquitin ligase cereblon (CRBN). It effectively recruits the CRBN protein for targeted protein degradation applications, facilitating the development of Proteolysis Targeting Chimeras (PROTACs). Its utility in research enables the selective modulation of protein levels, making it a valuable tool for studies in protein homeostasis and therapeutic development.
Product Information
Catalog NumA80566
FormulaC14H19ClN4O2
Molecular Weight310.78
CAS Number2446913-97-7
SMILESCl.O=C1NC(=O)CCN1C2=CC=C(C=C2)N3CCNCC3
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