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CRBN ligand-706

Ligand for E3 Ligase

CRBN ligand-706 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of CRBN to target proteins, enabling the development of proteolysis-targeting chimeras (PROTACs). CRBN ligand-706 serves as a valuable tool in research focused on targeted protein degradation and cellular regulation pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925103-45-1
Applications	Ligand for E3 Ligase
Formula	C₁₁H₉BrN₄O₃
Molecular Weight	325.12
SMILES	O=C1NC(=O)C(N2N=C3C=CC(Br)=CN3C2=O)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.