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CRBN ligand-710

Ligand for E3 Ligase

CRBN ligand-710 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), utilized to facilitate the recruitment of CRBN in targeted protein degradation. It can be conjugated to a specific target protein ligand through a linker, enabling the formation of PROTACs (proteolysis-targeting chimeras). This compound is instrumental in studies focusing on protein regulation and degradation pathways, thereby advancing research in cancer therapeutics and other diseases related to protein homeostasis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925100-36-1
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₃N₃O₅
Molecular Weight	303.27
SMILES	O=C(O)CN1C(=O)C2=CC=CC(=C2C1)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.