CRBN ligand-710

Catalog No.: A81226
Ligand for E3 Ligase
CRBN ligand-710 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), utilized to facilitate the recruitment of CRBN in targeted protein degradation. It can be conjugated to a specific target protein ligand through a linker, enabling the formation of PROTACs (proteolysis-targeting chimeras). This compound is instrumental in studies focusing on protein regulation and degradation pathways, thereby advancing research in cancer therapeutics and other diseases related to protein homeostasis.
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCRBN ligand-710 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), utilized to facilitate the recruitment of CRBN in targeted protein degradation. It can be conjugated to a specific target protein ligand through a linker, enabling the formation of PROTACs (proteolysis-targeting chimeras). This compound is instrumental in studies focusing on protein regulation and degradation pathways, thereby advancing research in cancer therapeutics and other diseases related to protein homeostasis.
Product Information
Catalog NumA81226
FormulaC14H13N3O5
Molecular Weight303.27
CAS Number2925100-36-1
SMILESO=C(O)CN1C(=O)C2=CC=CC(=C2C1)N3C(=O)NC(=O)CC3
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2