Fig. 1 · Structure

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CRBN ligand-714

Ligand for E3 Ligase

CRBN ligand-714 is an E3 ubiquitin ligase cereblon (CRBN) ligand that facilitates the recruitment of the cereblon protein. This compound can be utilized to develop PROTACs by linking it to a target protein ligand via a linker. CRBN ligand-714 is valuable in research focused on protein degradation and targeted protein modulation for therapeutic applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2925099-56-3
Applications Ligand for E3 Ligase
Formula C13H12N4O3
Molecular Weight 272.26
SMILES
O=CC1=CC(=CC2=NN(C=C21)C)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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