CRBN ligand-718 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein in cellular assays. This compound serves as a valuable tool for the development of proteolysis-targeting chimeras (PROTACs) by linking to a target protein ligand via a linker. Its applications include studying protein degradation pathways and creating innovative therapeutic strategies in targeted protein degradation research.
CRBN ligand-718 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein in cellular assays. This compound serves as a valuable tool for the development of proteolysis-targeting chimeras (PROTACs) by linking to a target protein ligand via a linker. Its applications include studying protein degradation pathways and creating innovative therapeutic strategies in targeted protein degradation research.
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