Documents & Downloads

CRBN ligand-721

Ligand for E3 Ligase

CRBN ligand-721 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), designed to facilitate the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a suitable linker, enabling the development of Proteolysis Targeting Chimeras (PROTACs). CRBN ligand-721 is valuable for research applications focused on targeted protein degradation and the modulation of cellular signaling pathways.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925095-05-0
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₂N₄O₃
Molecular Weight	272.26
SMILES	O=CC1=CC(=CC2=C1C=NN2C)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.