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CRBN ligand-722

Ligand for E3 Ligase

CRBN ligand-722 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound is designed for use in PROTAC (Proteolysis Targeting Chimeras) applications, enabling the effective degradation of target proteins through ubiquitin-proteasome pathways. Its versatility makes it a valuable tool for studying protein turnover and targeted protein modulation in various biological contexts.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925094-84-2
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₃N₃O₅
Molecular Weight	303.27
SMILES	O=C(O)CN1C(=O)C=2C(=CC=CC2C1)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.