CRBN ligand-727 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), serving to selectively recruit the cereblon protein. This compound can be conjugated to a target-specific protein ligand through a linker, facilitating the creation of a proteolysis-targeting chimera (PROTAC). Its applications lie in targeted protein degradation studies, enabling the investigation of protein function and modulation within various biological systems.
CRBN ligand-727 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), serving to selectively recruit the cereblon protein. This compound can be conjugated to a target-specific protein ligand through a linker, facilitating the creation of a proteolysis-targeting chimera (PROTAC). Its applications lie in targeted protein degradation studies, enabling the investigation of protein function and modulation within various biological systems.
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