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CRBN ligand-730

Ligand for E3 Ligase

CRBN ligand-730 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound is designed to be linked with a target protein ligand via a linker to generate a PROTAC (PROteolysis TArgeting Chimeras), which enhances targeted protein degradation. It serves as a valuable tool for research in protein interaction and degradation mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925072-83-7
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₂N₄O₃
Molecular Weight	272.26
SMILES	O=CC1=CC(=CC2=CN(N=C12)C)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.