CRBN ligand-749 serves as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the targeted recruitment of the cereblon protein. This compound can be conjugated with a target protein ligand through a linker, enabling the formation of a PROTAC (Proteolysis Targeting Chimera). Its primary applications include studying protein degradation pathways, and investigating the therapeutic potential of targeted protein modulation in various diseases.
CRBN ligand-749 serves as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the targeted recruitment of the cereblon protein. This compound can be conjugated with a target protein ligand through a linker, enabling the formation of a PROTAC (Proteolysis Targeting Chimera). Its primary applications include studying protein degradation pathways, and investigating the therapeutic potential of targeted protein modulation in various diseases.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
