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CRBN ligand-760

Ligand for E3 Ligase

CRBN ligand-760 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating its recruitment in cellular processes. This compound is instrumental in the development of proteolysis-targeting chimeras (PROTACs) by conjugating with target protein ligands through a linker. Its application in targeted protein degradation studies provides valuable insights into cellular regulation and therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925099-45-0
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₂N₄O₄
Molecular Weight	288.26
SMILES	O=C(O)C1=CC(=CC=2C=NN(C21)C)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.