CRBN ligand-763 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to a target protein ligand through a linker to generate a PROTAC (proteolysis-targeting chimera), enabling targeted protein degradation. It serves as a valuable tool in drug discovery and therapeutic research aimed at modulating protein levels within cells.
CRBN ligand-763 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to a target protein ligand through a linker to generate a PROTAC (proteolysis-targeting chimera), enabling targeted protein degradation. It serves as a valuable tool in drug discovery and therapeutic research aimed at modulating protein levels within cells.
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