CRBN ligand-770 is a novel ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. By linking CRBN ligand-770 to a target protein ligand through a suitable linker, researchers can construct proteolysis-targeting chimeras (PROTACs). This compound is valuable for investigating targeted protein degradation pathways and therapeutic strategies in cellular models.
CRBN ligand-770 is a novel ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. By linking CRBN ligand-770 to a target protein ligand through a suitable linker, researchers can construct proteolysis-targeting chimeras (PROTACs). This compound is valuable for investigating targeted protein degradation pathways and therapeutic strategies in cellular models.
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