CRBN ligand-787

Catalog No.: A80954
Ligand for E3 Ligase
CRBN ligand-787 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound can be utilized in the development of proteolysis-targeting chimeras (PROTACs) by linking it to a ligand for the target protein, enabling targeted degradation via the ubiquitin-proteasome system. CRBN ligand-787 is valuable in research applications focused on protein regulation and degradation mechanisms.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-787 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound can be utilized in the development of proteolysis-targeting chimeras (PROTACs) by linking it to a ligand for the target protein, enabling targeted degradation via the ubiquitin-proteasome system. CRBN ligand-787 is valuable in research applications focused on protein regulation and degradation mechanisms.
Product Information
Catalog NumA80954
FormulaC11H9ClN4O3
Molecular Weight280.67
CAS Number2154343-31-2
SMILESO=C1NC(=O)C(N2C(=O)C3=NC(Cl)=NC=C3C2)CC1
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