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CRBN ligand-796

Ligand for E3 Ligase

CRBN ligand-796 serves as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound is designed for use in PROTAC (PROteolysis TArgeting Chimeras) technology, allowing for the targeted degradation of proteins by linking to specific target protein ligands through a suitable linker. Its role in modulating protein degradation pathways makes it a valuable tool for research in targeted therapeutics and cellular signaling studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2573307-29-4
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₂BrN₃O₃
Molecular Weight	338.16
SMILES	O=C1N(C=2C(N1C)=CC=C(Br)C2)[C@@H]3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.