CRBN ligand-883

Catalog No.: A80574
Ligand for E3 Ligase
CRBN ligand-883 is a ligand that targets the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific protein partners. This compound can be utilized in the synthesis of PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. CRBN ligand-883 serves as a valuable tool for research applications aimed at studying targeted protein degradation and modulatory effects in cellular processes.
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Biological Activity
DescriptionCRBN ligand-883 is a ligand that targets the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific protein partners. This compound can be utilized in the synthesis of PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. CRBN ligand-883 serves as a valuable tool for research applications aimed at studying targeted protein degradation and modulatory effects in cellular processes.
Product Information
Catalog NumA80574
FormulaC12H11NO4
Molecular Weight233.22
CAS Number1502483-16-0
SMILESO=C(O)C1=CC=CC(=C1)C2C(=O)NC(=O)CC2
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