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CRBN ligand-883

Ligand for E3 Ligase

CRBN ligand-883 is a ligand that targets the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific protein partners. This compound can be utilized in the synthesis of PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. CRBN ligand-883 serves as a valuable tool for research applications aimed at studying targeted protein degradation and modulatory effects in cellular processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	1502483-16-0
Applications	Ligand for E3 Ligase
Formula	C₁₂H₁₁NO₄
Molecular Weight	233.22
SMILES	O=C(O)C1=CC=CC(=C1)C2C(=O)NC(=O)CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.