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CRBN ligand-887

Ligand for E3 Ligase

CRBN ligand-887 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound is designed to be linked to a target protein ligand through a linker, enabling the formation of a PROTAC (proteolysis-targeting chimera). It serves as a valuable tool in chemical biology for the selective degradation of target proteins, contributing to research in targeted protein regulation and degradation pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	56012-66-9
Applications	Ligand for E3 Ligase
Formula	C₅H₈N₄O₃
Molecular Weight	172.14
SMILES	O=C(N)NC1C(=O)NC(=O)NC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.