CRBN ligand-888 is a ligand for the E3 ubiquitin ligase cereblon (CRBN) that facilitates the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a linker, enabling the formation of a proteolysis-targeting chimera (PROTAC). Its application in targeted protein degradation research offers significant potential for therapeutic interventions in various diseases.
CRBN ligand-888 is a ligand for the E3 ubiquitin ligase cereblon (CRBN) that facilitates the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a linker, enabling the formation of a proteolysis-targeting chimera (PROTAC). Its application in targeted protein degradation research offers significant potential for therapeutic interventions in various diseases.
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