CRBN ligand-895-PEG2-N3

Catalog No.: A80109
E3 Ligase Ligand-linker Conjugate
CRBN ligand-895-PEG2-N3 is a synthetic E3 ligase ligand-linker conjugate designed to facilitate the development of PROTACs. This compound plays a crucial role in the targeted degradation of proteins by linking to E3 ligases, enhancing the specificity and efficacy of degradation processes. It serves as a valuable tool for researchers investigating protein modulation and therapeutic applications in targeted protein degradation strategies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCRBN ligand-895-PEG2-N3 is a synthetic E3 ligase ligand-linker conjugate designed to facilitate the development of PROTACs. This compound plays a crucial role in the targeted degradation of proteins by linking to E3 ligases, enhancing the specificity and efficacy of degradation processes. It serves as a valuable tool for researchers investigating protein modulation and therapeutic applications in targeted protein degradation strategies.
Product Information
Catalog NumA80109
FormulaC19H25N5O6
Molecular Weight419.43
CAS Number3052115-00-8
SMILESO=C(C(CC1)C2=CC=C(C=C2)OCC(NCCOCCOCCN=[N+]=[N-])=O)NC1=O
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