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CRBN ligand-895-PEG2-N3

E3 Ligase Ligand-linker Conjugate

CRBN ligand-895-PEG2-N3 is a synthetic E3 ligase ligand-linker conjugate designed to facilitate the development of PROTACs. This compound plays a crucial role in the targeted degradation of proteins by linking to E3 ligases, enhancing the specificity and efficacy of degradation processes. It serves as a valuable tool for researchers investigating protein modulation and therapeutic applications in targeted protein degradation strategies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3052115-00-8
Applications	E3 Ligase Ligand-linker Conjugate
Formula	C₁₉H₂₅N₅O₆
Molecular Weight	419.43
SMILES	O=C(C(CC1)C2=CC=C(C=C2)OCC(NCCOCCOCCN=[N+]=[N-])=O)NC1=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.