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CRBN ligand-895

E3 Ligase Ligand

CRBN ligand-895 is an E3 ubiquitin ligase ligand that specifically targets cereblon (CRBN), facilitating the recruitment of this crucial protein. This compound serves as a valuable building block for the synthesis of PROTACs, including PROTAC HDAC8 Degrader-4. Its application extends to the study of protein degradation pathways and the development of innovative therapeutic strategies in various disease models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2782024-56-8
Applications	E3 Ligase Ligand
Formula	C₁₇H₂₁NO₅
Molecular Weight	319.35
SMILES	O=C(C(CC1)C2=CC=C(C=C2)OCC(OC(C)(C)C)=O)NC1=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.