Fig. 1 · Structure
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CREB-IN-1 TFA
CREB Inhibitor
CREB-IN-1 TFA is a potent inhibitor of cAMP response element-binding protein (CREB), exhibiting an IC50 of 0.18 µM. This compound effectively inhibits the growth of breast cancer cells, making it a valuable tool for research in cancer biology and therapeutic development. Its ability to modulate CREB activity positions it as a significant candidate for studies focused on signal transduction pathways in oncogenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2912285-84-6 |
| Applications | CREB Inhibitor |
| Formula | C35H32ClF3N3O10P |
| Molecular Weight | 778.06 |
| SMILES | NCCCOC1=C(C=C2C=CC=CC2=C1)C(NCCOC3=CC4=CC=CC=C4C=C3C(NC5=CC=C(C=C5OP(O)(O)=O)Cl)=O)=O.OC(C(F)(F)F)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.