Fig. 1 · Structure

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CRF1 receptor antagonist-1

CRF1 Receptor Antagonist

CRF1 receptor antagonist-1 is a potent antagonist of the corticotropin-releasing factor 1 (CRF1) receptor. This compound is primarily utilized in research focusing on congenital adrenal hyperplasia (CAH) and related disorders. Its ability to inhibit CRF1 receptor activity may provide insights into stress response and endocrine regulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 2635364-30-4
Applications CRF1 Receptor Antagonist
Formula C27H28ClFN2O2S
Molecular Weight 499.04
SMILES
C#CCN(C1=NC(C2=C(C=C(C(C)=C2)OC)Cl)=C(S1)C)[C@H](C3=CC(F)=C(C=C3)CO)CC4CC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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