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Crizotinib-amide-PEG2-NH2

MET Ligand Llinker Conjugate

Crizotinib-amide-PEG2-NH2 is a MET ligand linker conjugate designed for targeted therapeutic applications. This compound facilitates the synthesis of the MET degrader OZD-MET 01, enabling the exploration of MET pathway modulation in cancer research. Its unique structure allows for enhanced delivery and efficacy in studies targeting MET-overexpressing tumors.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3048497-52-2
Applications	MET Ligand Llinker Conjugate
Formula	C₂₆H₃₁Cl₂FN₆O₄
Molecular Weight	581.47
SMILES	C[C@@H](OC1=CC(C2=CN(N=C2)C3CCN(C(OCCOCCN)=O)CC3)=CN=C1N)C4=C(Cl)C(F)=CC=C4Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.