Fig. 1 · Structure
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Crocetin
Anticancer/Neuroprotective Agent
Crocetin is a neuroprotective agent with strong affinity for NMDA receptors, which facilitates channel opening activity. It demonstrates significant anticancer properties by downregulating proinflammatory cytokines and COX-2 expression, while inhibiting apoptosis and MAPK activation. Crocetin's ability to penetrate the blood-brain barrier makes it a valuable compound for research applications in cancer, neurological disorders, and inflammation, particularly in studies related to cervical cancer and ischemia. Its potential to delay brain and body aging further underscores its importance in therapeutic investigations.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 27876-94-4 |
| Applications | Anticancer/Neuroprotective Agent |
| Formula | C20H24O4 |
| Molecular Weight | 328.40 |
| Synonyms | Transcrocetin |
| SMILES | O=C(O)/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.