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Crotonyl-CoA tetralithium

Derivative of CoA

Crotonyl-CoA tetralithium is a high-energy acyl donor and an important derivative of CoA involved in the metabolism of fatty acids and amino acids. It serves as a substrate for p300's histone crotonyltransferase activity, influencing global and gene-specific histone crotonylation levels, and plays a role in the regulation of gene expression. Additionally, Crotonyl-CoA tetralithium is utilized in the NADPH-mediated reduction and carbon dioxide trapping catalyzed by crotonyl-CoA reductase/carboxylase, contributing to the formation of alkylmalonyl-CoA polyketide synthase extender units. This compound is valuable for studies related to the LPS-induced inflammatory response.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Substrate
CAS Number	116912-55-1
Applications	Derivative of CoA
Formula	C₂₅H₄₀Li₄N₇O₁₇P₃S
Molecular Weight	863.37
SMILES	O[C@H]1[C@@H](O[C@@H]([C@H]1OP(O)(O)=O)COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(/C=C/C)=O)=O)=O)(O)=O)(O)=O)N2C3=NC=NC(N)=C3N=C2.[4Li]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.