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Crovozalpon

Alplha-1-antitrypsin Inhibitor

Crovozalpon is a potent inhibitor of alpha-1-antitrypsin, a crucial protein involved in regulating immune responses and inflammation. This compound can serve as a prodrug, presenting a pathway for enhanced bioavailability in therapeutic contexts. Crovozalpon is applicable in research exploring diseases associated with alpha-1-antitrypsin deficiency, including emphysema and liver disorders, by providing insights into potential interventions and disease mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2406205-67-0
Applications	Alplha-1-antitrypsin Inhibitor
Formula	C₂₀H₁₉ClF₂N₂O₃
Molecular Weight	408.83
SMILES	O[C@@H](C1=C(C(F)=CC=C1)Cl)[C@@H](CCC)NC(C2=C3C(NC(C3)=O)=C(C=C2)F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.