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CRT-0066101, potent inhibitor of protein kinase D (PKD); inhibits all PKD isoforms (IC50 values are 1, 2 and 2.5 nM for PKD1, PKD3 and PKD2 respectively).
| In vitro | DMSO | Warmed: 25 mg/mL (60.77 mM) | |
| Water | 80 mg/mL (194.49 mM) | ||
| Ethanol | Warmed: 2 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.31 mL | 121.56 mL | 243.11 mL |
| 0.5 mM | 4.86 mL | 24.31 mL | 48.62 mL |
| 1 mM | 2.43 mL | 12.16 mL | 24.31 mL |
| 5 mM | 0.49 mL | 2.43 mL | 4.86 mL |
*The above data is based on the productmolecular weight 411.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16318 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1883545-60-5 |
| Formula | C18H22N6O.2HCl |
| M. Wt | 411.33 |
| Purity | >98% |
| Synonyms | CRT 0066101, CRT0066101 |
| SMILES | Cl.Cl.Cn1cc(cn1)c3cc(c2nc(NC[[email protected]](N)CC)ccn2)c(O)cc3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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