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PKD Inhibitor

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Catalog No. A16318

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
CRT-0066101 5mg A16318-5
CRT-0066101 10mg A16318-10
CRT-0066101 50mg A16318-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

CRT-0066101, potent inhibitor of protein kinase D (PKD); inhibits all PKD isoforms (IC50 values are 1, 2 and 2.5 nM for PKD1, PKD3 and PKD2 respectively).


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Chemical Information

Catalog Num A16318
Actions Inhibitor
M. Wt 411.33
Formula C18H22N6O.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1883545-60-5
Synonyms CRT 0066101, CRT0066101
SMILES Cl.Cl.Cn1cc(cn1)c3cc(c2nc(NC[[email protected]](N)CC)ccn2)c(O)cc3

Biological Activity

CRT-0066101, potent inhibitor of protein kinase D (PKD); inhibits all PKD isoforms (IC50 values are 1, 2 and 2.5 nM for PKD1, PKD3 and PKD2 respectively).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.31 mL 121.56 mL 243.11mL
0.5 mM 4.86 mL 24.31 mL 48.62 mL
1 mM 2.43 mL 12.16 mL 24.31 mL
5 mM 0.49 mL 2.43 mL 4.86 mL

*The above data is based on the productmolecular weight 411.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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