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Cryptophycin 52

Anticancer Agent

Cryptophycin 52 is a synthetic 16-membered cyclic ester peptide derivative of the marine natural product cryptophycin 1, exhibiting potent antitumor activity. It primarily induces G2/M phase cell cycle arrest, rendering it effective against solid tumors, particularly those resistant to conventional chemotherapeutics such as Paclitaxel and Doxorubicin. This compound serves as a valuable tool for cancer research, especially in studies focused on multidrug-resistant tumors.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	186256-67-7
Applications	Anticancer Agent
Formula	C₃₆H₄₅ClN₂O₈
Molecular Weight	669.20
Synonyms	LY355703
SMILES	C[C@@H]([C@@]1([H])OC([C@@H](OC(C(C)(CNC([C@H](NC(/C=C/C1)=O)CC2=CC(Cl)=C(C=C2)OC)=O)C)=O)CC(C)C)=O)[C@]3([H])[C@@H](C4=CC=CC=C4)O3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.