Fig. 1 · Structure
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Cryptosporioptide A
Protein Tyrosine Phosphatases Iinhibitor
Cryptosporioptide A is a selective inhibitor of protein tyrosine phosphatases, specifically targeting enzymes such as PTP1B, SHP2, CDC25B, LAR, and SHP1. It demonstrates notable inhibitory activity, with IC50 values of 7.3, 5.7, 7.6, >50, and 4.9 μg/mL, respectively. This compound, derived from the insect-parasitic fungus Cordyceps gracilioides, is valuable for research applications focused on signaling pathways involved in cancer and metabolic diseases. Its ability to modulate phosphatase activity makes it a significant tool for investigating therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1647101-05-0 |
| Applications | Protein Tyrosine Phosphatases Iinhibitor |
| Formula | C18H17NO10 |
| Molecular Weight | 407.33 |
| SMILES | C[C@@]1([C@]23[C@](C(C4=C(O)C(C(O)=O)=CC=C4O3)=O)([H])[C@@](O)([C@@]1([H])OC(CC(N2)=O)=O)C)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.