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CSBP ligand 1

CSBP Ligand

CSBP Ligand 1 selectively binds to the CSBP target with an IC50 of 0.08 μM, demonstrating significant potency in modulating inflammatory responses. It effectively inhibits TNF production in LPS-treated murine models, highlighting its potential utility in studying inflammation-related conditions. CSBP Ligand 1 exhibits minimal inhibitory effects on PGHS-1 (IC50: 16 μM) and 5-LO (IC50: 60 μM), making it a valuable tool for researchers investigating the mechanisms of inflammation and potential therapeutic approaches.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	165806-32-6
Applications	CSBP Ligand
Formula	C₁₇H₁₄FN₃
Molecular Weight	279.31
SMILES	FC1=CC=C(C2=C(C3=CC=NC=C3)N(C4CC4)C=N2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.