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CSI118 TFA

Ligand for Target Protein for PROTAC

CSI118 TFA is a ligand for targeted protein degradation utilizing the PROTAC (Proteolysis Targeting Chimera) strategy. This compound has demonstrated the ability to effectively engage target proteins, facilitating their ubiquitination and subsequent proteasomal degradation. It serves as a valuable tool for researchers investigating targeted protein degradation mechanisms and developing novel therapeutic strategies. Additionally, CSI118 TFA can be utilized in the synthesis of CSI86, expanding its application in chemical biology research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3063898-01-8
Applications	Ligand for Target Protein for PROTAC
Formula	C₂₄H₁₉F₁₂N₃O₄
Molecular Weight	641.41
SMILES	O=C(C(F)(F)F)O.FC(F)(C1=NN(C)C(C2=C(O)C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=C(OCCCN)C=C2)=C1)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.