CSLP37 is a selective inhibitor of receptor-interacting protein kinase 2 (RIPK2), exhibiting an IC50 of 16.3 nM. This compound effectively suppresses cellular responses mediated by NOD1 and NOD2, while showing no significant inhibitory activity against RIPK1 and RIPK3. CSLP37 is a valuable tool for research into inflammatory signaling pathways and the role of RIPK2 in various diseases.
CSLP37 is a selective inhibitor of receptor-interacting protein kinase 2 (RIPK2), exhibiting an IC50 of 16.3 nM. This compound effectively suppresses cellular responses mediated by NOD1 and NOD2, while showing no significant inhibitory activity against RIPK1 and RIPK3. CSLP37 is a valuable tool for research into inflammatory signaling pathways and the role of RIPK2 in various diseases.
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