CST626

Name: CST626
Brand: Adooq Bioscience
SKU: A24498
Rating: 5 (288 reviews)

Catalog No.: A24498

IAP PROTAC degrader

CST626 (Compound 9) is a pan-IAP degrader PROTAC that targets and degrades inhibitor of apoptosis proteins XIAP, cIAP1, and cIAP2 in MM.1S cells, with DC₅₀ values of 0.7 nM, 2.4 nM, and 6.2 nM, respectively.

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Grouped product items
Size	Price	Stock
1mg	$360.00	In stock
5mg	$1,080.00	In stock
10mg	$1,840.00	In stock
50mg	$5,520.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	CST626 (Compound 9) is a pan-IAP degrader PROTAC that targets and degrades inhibitor of apoptosis proteins XIAP, cIAP1, and cIAP2 in MM.1S cells, with DC₅₀ values of 0.7 nM, 2.4 nM, and 6.2 nM, respectively.

Product Information

Catalog Num	A24498
Formula	C61H82N8O9S
Molecular Weight	1103.42
CAS Number	3033993-13-1
SMILES	O=C([C@H]1N(C([C@H](C2CCCCC2)NC([C@@H](NC)C)=O)=O)C[C@@H](OC3=CC=CC(OCCCCC(N[C@@H](C(C)(C)C)C(N4[C@H](C(N[C@H](C5=CC=C(C6=C(C)N=CS6)C=C5)C)=O)C[C@@H](O)C4)=O)=O)=C3)C1)N[C@@H]7CCCC8=C7C=CC=C8
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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