Fig. 1 · Structure
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CT-179
OLIG2 Inhibitor
CT-179 is an OLIG2 inhibitor that effectively disrupts dimerization, phosphorylation, and DNA binding of the OLIG2 protein. This compound demonstrates brain permeability and oral bioavailability, making it suitable for in vivo studies. CT-179 induces G2/M phase arrest and promotes apoptosis and differentiation in tumor cells, positioning it as a valuable tool for cancer research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1996636-69-1 |
| Applications | OLIG2 Inhibitor |
| Formula | C17H22Cl2N6O |
| Molecular Weight | 397.30 |
| SMILES | CC1=NC(NC(NC2=CC(Cl)=C(C=C2)Cl)=O)=NC(NCCCN(C)C)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.