Fig. 1 · Structure
Documents & Downloads
CT1113
USP28/USP25 Inhibitor
CT1113 is a selective inhibitor of USP28 and USP25, two deubiquitinating enzymes involved in protein regulation. This compound effectively reduces MYC protein levels, contributing to its anti-tumor activity. CT1113 demonstrates significant potential in cancer research, particularly in models of pancreatic cancer, where it has shown efficacy in reducing tumor growth.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2523435-18-7 |
| Applications | USP28/USP25 Inhibitor |
| Formula | C25H29N5O2S |
| Molecular Weight | 463.60 |
| SMILES | CNC1=C(C(N[C@@H]2CC3=CC=C(N4CC5NC(CC5)C4)C=C3OC2)=O)SC6=NC(C)=CC=C16 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.