Fig. 1 · Structure
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CTK7A
Anticancer Compound
CTK7A is a curcumin derivative that exerts anticancer effects by inhibiting the histone acetyltransferase (HAT) activity of p300, consequently reducing its autoacetylation. This action disrupts the interaction between p300 and HIF-1α, leading to decreased accumulation and activity of HIF-1α. CTK7A serves as a valuable tool for cancer research, particularly in studies exploring the modulation of hypoxia-related pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1297262-16-8 |
| Applications | Anticancer Compound |
| Formula | C28H23N2NaO6 |
| Molecular Weight | 506.48 |
| SMILES | COC(C=C1/C=C/C2=CC(/C=C/C3=CC(OC)=C(C=C3)O)=NN2C4=CC=C(C=C4)C(O[Na])=O)=C(C=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.