Fig. 1 · Structure

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CTR/AMYR agonist-1

CTR/AMYR Agonist

CTR/AMYR agonist-1 is a selective agonist for the Calcitonin Receptor (CTR) and Amylin Receptor (AMYR), exhibiting EC50 values ranging from 0.56 to 6.9 nM. This compound is instrumental in studying metabolic diseases, particularly in understanding the receptor-mediated pathways involved in energy homeostasis and glucose metabolism. Its high potency makes it a valuable tool for elucidating the physiological roles of CTR and AMYR in various biological contexts.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 3108097-26-0
Applications CTR/AMYR Agonist
Formula C34H37ClF2N8O4
Molecular Weight 695.16
SMILES
NC(C1=C(CC(C)C)N=C(N([C@H]2[C@H](CN(C3CC(F)(C3)F)CC2)OC)N=C4)C4=C1C5=CC=C(N(C(CO6)=O)CC7=NC=C(Cl)C=N7)C6=C5)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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