Fig. 1 · Structure
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Cu(II)-Elesclomol
Anticancer Agent
Cu(II)-Elesclomol is an anticancer agent formed by the complexation of Elesclomol with Cu2+ ions. It acts primarily as a weak inhibitor of DNA topoisomerase I, exerting its anticancer effects through the induction of oxidative stress and DNA damage via copper chelation. Cu(II)-Elesclomol effectively inhibits tumor cell proliferation, promotes cell cycle arrest, and triggers apoptosis, making it a valuable tool for cancer research and therapeutic investigations.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1224195-72-5 |
| Applications | Anticancer Agent |
| Formula | C19H18CuN4O2S2 |
| Molecular Weight | 462.05 |
| SMILES | CN1[N-](C(C2)=O)[Cu+2]([S]=C3C4=CC=CC=C4)([S]=C1C5=CC=CC=C5)[N-](C2=O)N3C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.