Curvularin

Catalog No.: A65123
NO Synthase Inhibitor
Curvularin is a potent inhibitor of inducible nitric oxide synthase (iNOS), demonstrating a half-maximal inhibitory concentration (IC50) of 9.5 µM. Isolated from the fungus Curvularia lunata, this mycotoxin is utilized in research to explore its effects on nitric oxide production in inflammatory responses. Curvularin's unique properties make it a valuable tool for investigating various biological processes and therapeutic applications related to iNOS inhibition.
Grouped product items
Size Price Stock Qty
1mg
$190.00
In stock
5mg
$485.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCurvularin is a potent inhibitor of inducible nitric oxide synthase (iNOS), demonstrating a half-maximal inhibitory concentration (IC50) of 9.5 µM. Isolated from the fungus Curvularia lunata, this mycotoxin is utilized in research to explore its effects on nitric oxide production in inflammatory responses. Curvularin's unique properties make it a valuable tool for investigating various biological processes and therapeutic applications related to iNOS inhibition.
Product Information
Catalog NumA65123
FormulaC16H20O5
Molecular Weight292.33
CAS Number10140-70-2
SMILESO=C(O[C@@H](C)CCCCC1)CC2=CC(O)=CC(O)=C2C1=O
Synonyms(S)-Curvularin
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