Documents & Downloads

Cusculine

OROV Endonuclease Inhibitor

Cusculine is a potent endonuclease inhibitor specifically targeting the Oropouche virus (OROV) with an IC50 of 1.4 μM. It effectively disrupts the interaction between OROV endonuclease and viral RNA, potentially hindering protein interactions necessary for replication. By intercalating into double-stranded RNA, a critical intermediate in the viral life cycle, Cusculine demonstrates significant efficacy in inhibiting OROV replication in vitro. This compound is a valuable tool for research into Oropouche fever and related virology studies.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	143438-95-3
Applications	OROV Endonuclease Inhibitor
Formula	C₁₈H₁₉NO₆
Molecular Weight	345.35
Synonyms	FAC21
SMILES	O=C1C2=CC=C(OC)C(OC)=C2NC3=CC(OC)=C(OC)C(OC)=C13

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.