Fig. 1 · Structure
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Cuspin-1
SMN Upregulator
Cuspin-1 is a potent upregulator of Survival of Motor Neuron (SMN) protein, known for enhancing SMN expression through post-transcriptional mechanisms. Additionally, it increases the phosphorylation of Erk, linking it to key signaling pathways involved in neuronal health. This compound is primarily utilized in research related to neurodegenerative diseases, particularly spinal muscular atrophy (SMA), making it a valuable tool for studies aimed at understanding and developing therapies for these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 337932-29-3 |
| Applications | SMN Upregulator |
| Formula | C13H10BrNO |
| Molecular Weight | 276.13 |
| SMILES | CC1=CC=C(C=C1)C(C2=CC(Br)=CN=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.