CVN636

Catalog No.: A61749
mGluR7 Allosteric Agonist
CVN636 is a selective allosteric agonist of the metabotropic glutamate receptor 7 (mGluR7) with an EC50 value of 7 nM for human mGluR7. This compound exhibits significant central nervous system (CNS) permeability, making it a valuable tool for exploring mGluR7 modulation. Its potent activity supports research applications in the investigation of neurological disorders and the pharmacological profiling of mGluR7-related pathways.
Grouped product items
Size Price Stock Qty
1mg
$225.00
In stock
5mg
$560.00
In stock
10mg
$940.00
In stock
25mg
$1,880.00
In stock
50mg
$2,950.00
In stock
100mg
$4,610.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCVN636 is a selective allosteric agonist of the metabotropic glutamate receptor 7 (mGluR7) with an EC50 value of 7 nM for human mGluR7. This compound exhibits significant central nervous system (CNS) permeability, making it a valuable tool for exploring mGluR7 modulation. Its potent activity supports research applications in the investigation of neurological disorders and the pharmacological profiling of mGluR7-related pathways.
Product Information
Catalog NumA61749
FormulaC19H20FNO4S
Molecular Weight377.43
CAS Number2226732-62-1
SMILESCS(=O)([C@H]1C2=CC=CC=C2OC[C@@H]1NC([C@H](C3=CC=C(C=C3)F)C)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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