Fig. 1 · Structure
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CVN636
mGluR7 Allosteric Agonist
CVN636 is a selective allosteric agonist of the metabotropic glutamate receptor 7 (mGluR7) with an EC50 value of 7 nM for human mGluR7. This compound exhibits significant central nervous system (CNS) permeability, making it a valuable tool for exploring mGluR7 modulation. Its potent activity supports research applications in the investigation of neurological disorders and the pharmacological profiling of mGluR7-related pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2226732-62-1 |
| Applications | mGluR7 Allosteric Agonist |
| Formula | C19H20FNO4S |
| Molecular Weight | 377.43 |
| SMILES | CS(=O)([C@H]1C2=CC=CC=C2OC[C@@H]1NC([C@H](C3=CC=C(C=C3)F)C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.