Fig. 1 · Structure
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Cyclic ADP-ribose
Ca+-Mobilization Messenger
Cyclic ADP-ribose (cADPR) serves as a critical second messenger involved in calcium mobilization, synthesized from NAD+ by ADP-ribosyl cyclase. It primarily functions by facilitating the release of calcium from the endoplasmic reticulum through Ryanodine receptors and also contributes to extracellular calcium influx via the activation of TRPM2 channels. cADPR is instrumental in various cellular signaling processes, making it valuable for research related to calcium signaling pathways and their implications in physiological and pathological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 119340-53-3 |
| Applications | Ca+-Mobilization Messenger |
| Formula | C15H21N5O13P2 |
| Molecular Weight | 541.30 |
| Synonyms | cADPR |
| SMILES | O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N(C=N3)[C@@H]([C@H](O)[C@@H]4O)O[C@@H]4CO5)=N)O[C@@H]1COP(OP5(O)=O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.