Cyclic L27-11 is a cyclic peptide antibiotic primarily targeting bacterial outer membrane protein LptD. It exhibits potent nanomolar antibacterial activity against Pseudomonas species, particularly Pseudomonas aeruginosa. By disrupting the transport of lipopolysaccharide (LPS), Cyclic L27-11 leads to the accumulation of membrane-like substances within bacterial cells, ultimately impacting bacterial viability. This compound serves as a valuable tool in the development of new antibacterial agents.
Cyclic L27-11 is a cyclic peptide antibiotic primarily targeting bacterial outer membrane protein LptD. It exhibits potent nanomolar antibacterial activity against Pseudomonas species, particularly Pseudomonas aeruginosa. By disrupting the transport of lipopolysaccharide (LPS), Cyclic L27-11 leads to the accumulation of membrane-like substances within bacterial cells, ultimately impacting bacterial viability. This compound serves as a valuable tool in the development of new antibacterial agents.
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