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Cyclic(YCDGFYACYMDV)

HER2 Inhibitor

Cyclic(YCDGFYACYMDV) is a selective inhibitor of the HER2 signaling pathway, exhibiting significant anti-cancer activity. This compound self-assembles into nanoparticles in aqueous environments and converts into nanofibers upon specific binding to HER2 on tumor cells, effectively disrupting HER2 dimerization and downstream signaling, thereby inducing apoptosis. Its inhibitory effects on HER2-positive breast cancer have been validated in murine xenograft models, making it a valuable tool for cancer research and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	535959-77-4
Applications	HER2 Inhibitor
Formula	C₆₅H₈₂N₁₂O₂₀S₃
Molecular Weight	1447.61
SMILES	[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)CC(O)=O)=O)CCSC)=O)NC(=O)[C@H]2NC(=O)[C@H](C)NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC([C@H](CC5=CC=C(O)C=C5)N)=O)CSSC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.