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Cyclo(Arg-Gly-Asp-D-Phe-Val)

αvβ3 Inhibitor

Cyclo(Arg-Gly-Asp-D-Phe-Val) is an integrin αvβ3 inhibitor that exhibits significant antitumor activity. This cyclic peptide is primarily utilized in research related to acute myeloid leukemia and other cancer models, contributing to the understanding of tumor cell behavior and therapeutic strategies. Its ability to disrupt αvβ3 interactions makes it a valuable tool in cancer research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	137813-35-5
Applications	αvβ3 Inhibitor
Formula	C₂₆H₃₈N₈O₇
Molecular Weight	574.63
Synonyms	Cyclo(RGDfV); C(RGDfV)
SMILES	C([C@H]1NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC1=O)C2=CC=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.