Cycloneroside D

Catalog No.: A65247
NO Synthase Inhibitor
Cycloneroside D is a novel sesquiterpene aminoglycoside identified from the deep-sea fungus Trichoderma sp. SCSIOW21, serving as a nitric oxide synthase inhibitor. It demonstrates significant anti-inflammatory activity, with an IC50 value of 42.0 μM for nitric oxide production inhibition in RAW 264.7 macrophage cells. This compound is suitable for research applications focusing on inflammatory pathways and nitric oxide-related signaling.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCycloneroside D is a novel sesquiterpene aminoglycoside identified from the deep-sea fungus Trichoderma sp. SCSIOW21, serving as a nitric oxide synthase inhibitor. It demonstrates significant anti-inflammatory activity, with an IC50 value of 42.0 μM for nitric oxide production inhibition in RAW 264.7 macrophage cells. This compound is suitable for research applications focusing on inflammatory pathways and nitric oxide-related signaling.
Product Information
Catalog NumA65247
FormulaC23H39NO8
Molecular Weight457.56
CAS Number3075431-07-8
SMILESC[C@@]1([C@@]2([H])[C@@H](C(CO[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)NC(C)=O)=CC2)C)O[C@H](CC1)C(C)(O)C
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