Fig. 1 · Structure
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Cyclopentenylcytosine
CTP synthetase Inhibitor
Cyclopentenylcytosine is a potent inhibitor of CTP synthetase, leading to the depletion of CTP and dCTP pools. This compound demonstrates broad-spectrum antiviral activity against both DNA and RNA viruses, and has been shown to enhance the radiosensitization effect of Gemcitabine in human pancreatic cancer cells. Additionally, Cyclopentenylcytosine exhibits effective antiviral properties in the Ad5/NZW rabbit ocular replication model and shows anti-tumor activity in various tumor xenograft models. It is a valuable reagent for research in virology and oncology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 90597-22-1 |
| Applications | CTP synthetase Inhibitor |
| Formula | C10H13N3O4 |
| Molecular Weight | 239.23 |
| Synonyms | CPEC; NSC 375575 |
| SMILES | O[C@H]1[C@H](N2C(N=C(N)C=C2)=O)C=C(CO)[C@H]1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.