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Cyclopropenone probe 1

GSTP1 Inhibitor

Cyclopropenone probe 1 is a selective inhibitor of glutathione S-transferase pi-1 (GSTP1), which plays a critical role in the progression of triple-negative breast cancer. This compound covalently modifies GSTP1 at its catalytic active site, providing insights into its biological function and potential therapeutic targeting. Additionally, Cyclopropenone probe 1 serves as a click chemistry reagent, featuring an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules for advanced research applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2771119-22-1
Applications	GSTP1 Inhibitor
Formula	C₁₂H₈O₂
Molecular Weight	184.19
SMILES	C#CCOC1=CC=C(C=C1)C2=CC2=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.