Fig. 1 · Structure

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CYP19A1-IN-1

Cat. No. A69847 CAS 889959-22-2

CYP19A1 Inhibitor

CYP19A1-IN-1 is a selective inhibitor of CYP19A1, exhibiting an IC50 of 271 nM. By binding to CYP19A1, it effectively inhibits the conversion of androgens to estrogens. This reagent is valuable for research applications focused on estrogen-dependent diseases, including breast cancer, enabling studies on hormone regulation and potential therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 889959-22-2
Applications CYP19A1 Inhibitor
Formula C21H16ClN3O3
Molecular Weight 393.82
SMILES
CC(C1=CC=C(C=C1)N2C=CN=C2)NC(C3=CC4=CC(Cl)=CC=C4OC3=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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